Table 5: Regression slopes with p-values by age and gender for the models fitted for log10 transformed values of thyroid stimulating hormone (TSH in nIU/mL), free triiodothyronine (FT3 in fg/mL), free thyroxin (FT4 in pg/dL), total triiodothyronine (TT3 in pg/dL), total thyroxin (TT4 in ng/mL), and thyroglobulin (TGN in fg/mL) when association with urine lead was investigated. Data from National Health and Nutrition Examination Survey 2007-2012. Statistically significant slopes are displayed in bold letters.
| Gender: IOS | Independent variable | TSH | FT3 | FT4 | TT3 | TT4 | TGN |
|---|---|---|---|---|---|---|---|
| Male: IOD* | Log10 of Urine Lead | 0.0953369519 (0.11) | 0.001840619 (0.72) | -0.023835145 (0.02) | 0.0025197556 (0.81) | -0.008671475 (0.35) | 0.0153603499 (0.78) |
| NHANES survey cycle | 0.00778842 (0.71) | -0.004064014 (0.19) | 0.013635186 (0) | -0.002955405 (0.56) | -0.00896487 (0.06) | 0.0133139461 (0.5) | |
| Log10 of Urine Creatinine | -0.086948445 (0.16) | 0.0160065483 (0.07) | 0.0174653237 (0.14) | 0.0164875274 (0.22) | 0.0080016924 (0.49) | 0.1291737626 (0.08) | |
| R2 in percent | 2.2 | 30.6 | 7.0 | 17.2 | 5.1 | 10.5 | |
| Male: IOR* | Log10 of Urine Lead | 0.0410074728 (0.1) | -0.004712712 (0.33) | -0.024040038 (0.01) | 0.0039154333 (0.56) | -0.015953964 (0.05) | 0.0517085591 (0.16) |
| NHANES survey cycle | -0.001768468 (0.87) | -0.003666564 (0.19) | 0.0085708044 (0.05) | 0.0002098628 (0.96) | -0.011986282 (0) | 0.0012280675 (0.93) | |
| Log10 of Urine Creatinine | -0.044428942 (0.4) | 0.0146126729 (0.06) | 0.0183813787 (0.13) | 0.0075758394 (0.46) | 0.0064332484 (0.7) | -0.087538719 (0.16) | |
| R2 in percent | 6.1 | 30.8 | 6.1 | 20.5 | 5.7 | 6.0 | |
| Female: IOD* | Log10 of Urine Lead | 0.0001457806 (1) | -0.023101706 (0.01) | 0.0107963267 (0.36) | -0.02725571 (0.02) | -0.009828297 (0.42) | 0.023556915 (0.7) |
| NHANES survey cycle | 0.0013230706 (0.94) | -0.002343581 (0.25) | 0.0157923713 (0) | 0.0006743429 (0.85) | -0.008096723 (0.09) | -0.004495262 (0.82) | |
| Log10 of Urine Creatinine | -0.012920841 (0.78) | 0.0219270083 (0.01) | -0.006418433 (0.67) | 0.0289782561 (0.04) | -0.000072435 (1) | -0.05737875 (0.37) | |
| R2 in percent | 9.5 | 20.0 | 6.0 | 8.6 | 12.4 | 8.8 | |
| Female: IOR* | Log10 of Urine Lead | -0.022938005 (0.59) | -0.007028532 (0.27) | 0.0011231727 (0.88) | -0.021506431 (0.04) | -0.017114036 (0.16) | -0.038422486 (0.56) |
| NHANES survey cycle | 0.0042268246 (0.69) | -0.001479838 (0.58) | 0.0140811206 (0) | 0.0050989341 (0.34) | -0.006420846 (0.18) | -0.00008967 (1) | |
| Log10 of Urine Creatinine | -0.078257244 (0.09) | 0.0256713699 (0.01) | 0.0044048337 (0.7) | 0.0267121505 (0.13) | 0.0074417583 (0.67) | 0.0430685262 (0.63) | |
| R2 in percent | 10.2 | 23.3 | 7.6 | 13.7 | 6.5 | 7.1 |
*IOD = Iodine Deficient or urine iodine < 100 ng/mL; IOR = Iodine Replete or urine iodine ≥ 100 ng/mL.