Table 3: Memory impairments after ∆9-THC administration in humans
Subjects |
THC dose |
Memory impairment |
Study |
Healthy volunteers |
Δ9-THC (2.5 and 5 mg, i.v.) |
Impaired immediate and delayed word recall, verbal fluency and working memory. |
[10] |
Infrequent cannabis users |
Δ9-THC (15 mg and 7.5 mg, orally) |
Impaired episodic memory and learning (dose-dependent). |
[82] |
Healthy volunteers, with a history of light cannabis use |
Δ9-THC –dominant cannabis (125 mg by vaporization) |
Impaired driving during a car-following task ¯ Confidence in driving Acute cognitive impairment. |
[83] |
Healthy, occasional cannabis users |
Δ9-THC (300 μg/kg, single dose by vaporization) |
Immediate false-memories |
[84] |
Healthy, nondependent but experienced, cannabis users |
66.67 mg Bedrobinol (16.1% THC and <1% CBD) using ‘joints’, |
Impaired verbal and working memory. |
[71] |
Cannabis users |
Δ9-THC 8 mg or Δ9-THC 8 mg + CBD 16 mg (by inhalation through a vaporizer). |
Impaired episodic and working memory |
[57] |