Table 3: Memory impairments after ∆9-THC administration in humans

Subjects

THC dose

Memory impairment

Study

Healthy volunteers

Δ9-THC (2.5 and 5 mg, i.v.)

Impaired immediate and delayed word recall, verbal fluency and working memory.

[10]

Infrequent cannabis users

Δ9-THC (15 mg and 7.5 mg, orally)

Impaired episodic memory and learning (dose-dependent).

[82]

Healthy volunteers, with a history of light cannabis use

Δ9-THC –dominant cannabis (125 mg by vaporization)

Impaired driving during a car-following task

¯ Confidence in driving

Acute cognitive impairment.

 [83]

Healthy, occasional

cannabis users

Δ9-THC (300 μg/kg, single dose by vaporization)

­ Immediate false-memories

[84]

Healthy, nondependent but experienced, cannabis users

66.67 mg Bedrobinol (16.1% THC and <1% CBD) using ‘joints’,

Impaired verbal and working memory.

[71]

Cannabis users

Δ9-THC 8 mg or Δ9-THC 8 mg + CBD 16 mg (by inhalation through a vaporizer).

Impaired episodic and working memory

[57]