Table 2: Case reports involving mirtazapine induced serotonin syndrome.
Author (s) | Medications | Key symptoms | Treatment | Clinical outcome (s) |
Demers, et al. [11] | Mirtazapine and fluoxetine | Tremor, restlessness, flushing and diaphoresis | Discontinuation of medication | Complete recovery |
Hernandez, et al. [12] | Mirtazapine alone | Hypertension, altered mental state, myoclonus and hyperreflexia | Discontinuation of medication | Recovery with mild persistent rigidity |
Duggal, et al. [13] | Mirtazapine, olanzapine and tramadol | Confusion, tachycardia, tremors, ataxia, hyperreflexia and myoclonus | Discontinuation of medication | Complete recovery |
Houlihan, et al. [14] | Mirtazapine, tramadol and venlafaxine | Tachycardia, altered mental state, myoclonus and hyperreflexia | Discontinuation of medication | Complete recovery |