Open Access DOI:10.23937/2572-3243.1510009
Radiographic Follow-up of Transforaminal Lumbar Fusion with Silicon Nitride Spacers: A case Report of Two Patients
Jim A Youssef, Sue Lynn Myhre and B. Sonny Bal
Article Type: Original Article | First Published: March 28, 2016
When non operative actions for degenerative spinal disorders fall flat, surgical intervention frequently becomes the popular choice of treatment. Although the class of pathology matters, the surgical operation will generally include an arthrodesis procedure. The gravity of a successful initial fusion surgery is intensified not only by the growing number of arthrodesis procedures, but also by the rising costs for revisal operations. Additionally, fusion success appears to have an impact on patien...
Open Access DOI:10.23937/2572-3243.1510008
Bone Mineral Density Measured by Quantitative Computed Tomography in pre-pubertal/Early Pubertal children with hypovitaminosis D
Ferenc Peter, Agota Muzsnai, Laszlo Blatniczky and Peter Lakatos
Article Type: Original Article | First Published: March 28, 2016
These examinations were performed in pre-pubertal and early pubertal white European children living in one of the inner Buda districts of Budapest. This region of the city is populated by slightly more well-to-do families than the average. The selection was made in two schools. All parents of studied children provided written informed consent, enrollment included more than 90% of children in the chosen classes. To avoid the effects of pubertal changes as far as possible, the upper age-limit was ...
Open Access DOI:10.23937/2572-3243.1510007
Immune-mediated Mechanisms and Immunotherapy of Duchenne Muscular Dystrophy
Ruojie He and Cheng Zhang
Article Type: Review Article | First Published: March 01, 2016
The immune response is a critical mechanism for dystrophic muscle pathology and muscle wasting in Duchenne Muscular Dystrophy (DMD). The inflammatory processes are supposed to associate with activation of the innate immune response like macrophages infiltration, T cell-mediated immune response, generation of cytokines and chemokines and the aberrant activation of NF-kB signaling pathway, which contribute to severe muscle necrosis and fibrosis....
