Esophago-Pulmonary Fistula Caused by Lung Cancer Treated with a Covered Self-Expandable Metallic Stent
Takashi Abe, Takayuki Nagai and Kazunari Murakami
Article Type: Clinical Image | First Published: December 01, 2016
A 71-year-old man was diagnosed with squamous cell lung cancer in the right lower lobe. He was treated with chemotherapy (first line: TS-1/CDDP; second line: carboplatin/nab-paclitaxel) and radiation therapy (41.4 Gy), but his disease continued to progress. The patient complained of relatively sudden-onset chest pain and high-grade fever. Computed tomography (CT) showed a small volume of air in the lung cancer of the right lower lobe, so the patient was suspected of fistula between the esophagus...
Rare Delayed Metastasis of Uveal Melanoma Presenting as Fulminant Liver Failure
Natalia G Vallianou, Charikleia Kouvidou, Eleni Geladari, Kyriakos Trigkidis, Eleni Antypa and Evangelos Kokkinakis
Article Type: Case Report | First Published: November 09, 2016
Uveal melanoma is the most common primary intraocular malignant tumor in adult. Here, we present a patient who died due to hepatic encephalopathy, which was attributed to liver metastasis, which occurred nine years after the revelation of the uveal melanoma....
Portal Hypertension Does Not Preclude the Efficacy of Direct-acting Anti-Hepatitis C Viral Therapy
Kazuhiko Morii, Takeharu Yamamoto, Shinichiro Nakamura, Mitsuki Fukumoto, Reiko Iwamoto, Mai Yoshioka and Hiroaki Okushin
Article Type: Research Article | First Published: October 24, 2016
Purpose: This study aimed to investigate whether patients with hepatitis C virus (HCV)-related cirrhosis and clinically significant portal hypertension (CSPH) could show satisfactory virological and safety outcomes on direct-acting antiviral (DAA) therapy. Methods: Patients with HCV-related cirrhosis treated with DAA therapy were collected in the period between December 2014 and December 2015. Patient characteristics, therapeutic details, and safety outcomes were evaluated. CSPH was defined as p...
Extrahepatic Portal Vein Obstruction in the Pediatric Age: A Medical Challenge
Parisa Khodayar-Pardo and Andres Pena Aldea
Article Type: Mini Review | First Published: October 04, 2016
Extrahepatic portal vein obstruction (EHPVO), although rare in children, is a significant cause of portal hypertension (PHT) which leads to life-threatening gastrointestinal bleeding in the pediatric age group. PHT may also lead to other complications such as hypersplenism, cholangiopathy, ascites, and even hepatopulmonary syndrome and portopulmonary hypertension that may require organ transplantation....
Current Status of Colorectal Cancer: From Prevention to Treatment
Maite Dominguez-Ayala, Alberto Loizate Totoricaguena, Izaskun del Hoyo Aretxabala, Beatriz Uriarte Vergara, Inigo Vilar Achabal and Jesus Maria Gomez Zabala
Article Type: Research Article | First Published: October 04, 2016
The management process of colorectal cancer (CRC) comprises a large number of strategic moments for disease treatment. Key points of progress on this disease research range from the the initial screening phase, where screening tests and maximum population coverage are crucial, to the decision on what is the best personalized treatment at different disease stages. An overview of each of these phases will be conducted, unifying in one article the two main moments of CRC management....