Coexistence of Acute Appendicitis and Perforated Meckel's Diverticulitis: A Rare Presentation in Older Adults
Rahman Senocak, Mehmet Ince, Sahin Kaymak, Zafer Kilbas and M Tahir Ozer
Article Type: Case Report | First Published: February 12, 2016
An appendectomy is one of the most commonly performed abdominal surgical procedures. During this operation, a Meckel's diverticulum (MD) can occasionally be found as an incidental finding, but the coexistence of both appendicitis and a perforated MD is fairly rare. Complications associated with an MD commonly occur in males, but the frequency of complications decreases with aging. Here, we present a rare case with a simultaneous coexistence of appendicitis and a perforated MD in an older patient...
Giant Gastric Heterotopia in the Duodenum of an Adolescent Male and Review of the Literature
Laura El-Hage, Vinay Sood and Cary Qualia
Article Type: Case Report | First Published: February 11, 2016
Duodenal polyps are typically found during routine screening esophagogastroduodenoscopy for patients who have known hereditary polyposis syndromes. When polyps enlarge they may cause obstruction of the gastrointestinal tract, which is rare. We report an adolescent male without history of an underlying polyposis syndrome found to have multiple duodenal polyps comprised of gastric tissue during an upper endoscopy performed for vomiting....
Diagnosis and Management of Helicobacter pylori
Uni Wong and Leon P McLean
Article Type: Original Article | First Published: February 02, 2016
Helicobacter pylori is a common infection linked to dyspepsia, peptic ulcer disease, gastritis, gastric cancer, and MALT lymphoma. Endoscopic and nonendoscopic options may be used to diagnose H. pylori and confirm its eradication. Fourteen days of triple or quadruple therapy may be used as initial therapy, although clarithromycin-based triple therapy has become less effective over time....
Minimal Change Nephrotic Syndrome and Hodgkin's Lymphoma Associated with Adalimumab Therapy
James Brief, Anupama Chawla, Kathleen Usmani, Grace Gathungu, Robert Woroniecki, Daniel Coldren and Jeffrey Morganstern
Article Type: Case Report | First Published: February 02, 2016
The patient is a 16 year-old male with CD and no family history of IBD, nephrotic disease or hypertension. CD was diagnosed at age 15 after intestinal biopsies demonstrated severe disease in the terminal ileum, ascending and transverse colon. Initial attempts to treat his disease with 5-aminosalicylic acid (800 mg mesalamine TID) and 6-mercaptopurine (both 50 mg and 75 mg daily) were ineffective in controlling his gastrointestinal symptoms....
Are Patients Hospitalized with Cirrhosis and Ascites Receiving Appropriate Diagnostic Paracentesis?
Harith Baharith, Yuhong Yuan and Marco Puglia
Article Type: Research Article | First Published: February 16, 2016
Ascites is the most common complication of cirrhosis, and is associated with increased mortality. Diagnostic paracentesis is recommended for patients who are admitted to the hospital with ascites. However, it is unknown if diagnostic paracentesis in Canadian teaching hospitals are done according to recommended guidelines. We analyzed the rate of paracentesis, determined barriers for not performing paracentesis and the association of not performing paracentesis with mortality....
Eradication of Helicobacter Pylori Infection: Past, Present and Future
Baryshnikova NV, Uspenskiy YP and Suvorov AN
Article Type: Review Article | First Published: January 26, 2016
This review is a comprehensive summary of different variants of anti-Helicobacter pylori therapy from past strategies to the current state of the art. Nowadays we see a progressive decreasing of eradication rate in many countries in case of use standard triple therapy. It can be associated with high clarithromycin resistance of Helicobacter pylori. Gradual increase in number of the used antibiotics, the increase in duration of treatment, use of new antibacterial compounds and schemes of treatmen...
Advances and Controversies in the Management of Locally Advanced Gastro-esophageal Adenocarcinoma
Hirva Mamdani, Kenneth A Kesler and Shadia I Jalal
Article Type: Review Article | First Published: January 09, 2016
Esophageal adenocarcinoma (EAD) has been recently described as 'the silent epidemic' because of its rapidly rising incidence. Two-thirds of patients with esophageal adenocarcinoma present with locally advanced disease. In spite of recent advances in cancer therapy, the treatment of locally advanced esophageal and gastroesophageal junction (GEJ) adenocarcinoma remains challenging. Current standard of care for fit patients with locally advanced esophageal adenocarcinoma is trimodality therapy with...
Endoscopic Retrograde Cholangiopancreatography in Pediatric Biliary Diseases
Paola De Angelis, Renato Tambucci, Giulia Angelino, Filippo Torroni, Francesca Rea, Giovanni Federici di Abriola, Francesca Foschia, Tamara Caldaro, Simona Faraci, Anna Chiara Contini, Erminia Romeo and Luigi Dall'Oglio
Article Type: Review Article | First Published: January 04, 2016
Endoscopic retrograde colangio-pancreatography (ERCP) in children is currently widespread and utilized, particularly for therapeutic indication, as in adulthood. ERCP considered efficacy and safe in children, if performed by expert endoscopists. In the last year, the incoming progress of magnetic resonance image (MRI), especially in collaborator pediatric patients, eliminated many diagnostic indications for ERCP, leaving therapeutic aims as in adults....