Open Access DOI:10.23937/2469-567X/1510021
Comprehensive Programme to Prevent Cervical Cancer - the Case of Hungary
Dobrossy L, Oroszi B, Kovacs A and Budai A
Article Type: Case Report | First Published: April 30, 2016
The overall purpose of a comprehensive cervical cancer prevention programme is to coordinate HPV vaccination (primary prevention) and cervical screening (secondary prevention). Harmonization of the HPV vaccination and population screening is expected to reduce the burden of cervical cancer by reducing human papillomavirus (HPV) infections, and detecting cervical pre-cancer lesions and invasive cancer earlier, providing timely treatment. In 2015, 80% of 7th class schoolgirls between 12-13 years o...
Open Access DOI:10.23937/2469-567X/1510020
PrEP Works, But Only When You [Have Access to] Take it: Improving PrEP Access for Young People in Chicago and Philadelphia
S Caitlin Conyngham, Cassie R Warren and Helen C Koenig
Article Type: Commentary | First Published: March 31, 2016
The 2012 United States Food and Drug Administration approval of Tenofovir/Emtricitabine for HIV pre-exposure prophylaxis (PrEP) has added a highly effective, safe biomedical option to the HIV prevention toolbox. In the United States, young black and Latino men who have sex with men (MSM) and transgender women are disproportionately affected by HIV risk over the course of their lifetime. Nearly 1 in 10 black MSM under age 25 is infected with HIV every year, and there are more new HIV infections a...
Open Access DOI:10.23937/2469-567X/1510019
Non Alcoholic Fatty Liver Disease and Bone Fractures in Patients with HIV
Pollo-Flores P, BicudoA, Cruz-FilhoR and Soares DV
Article Type: Short Review | First Published: March 31, 2016
Human immunodeficiency virus infection has posed a challenge for mankind and now this disease is more of a challenge for quality of life than for virus related mortality. This review aims to study two prevalent diseases that may affect this population by decreasing their quality of life. Bone fractures are much more common in the HIV-positive population and have many etiopathogenesis implicated. Non-alcoholic fatty liver disease is also common in HIV-positive patients and may even lead to cirrho...
Open Access DOI:10.23937/2469-567X/1510018
Nucleoside Reverse Transcriptase Inhibitor (NRTI) Associated Macrocytosis
Wesley D. Kufel, Cory M. Hale, Eric F. Sidman, Cesar E. Orellana and Christopher D. Miller
Article Type: Short Review | First Published: March 31, 2016
Macrocytosis has been associated with several disease states, vitamin deficiencies, and medications, with nucleoside reverse transcriptase inhibitors (NRTIs) being a less commonly identified cause. NRTIs are frequently utilized as the two-drug backbone for the treatment of Human Immunodeficiency Virus (HIV). Amongst the NRTI drug class, zidovudine (AZT) and stavudine (d4T) are the most widely reported cause of macrocytosis. Fortunately, AZT and d4T have become less commonly used therapies, as ne...
Open Access DOI:10.23937/2469-567X/1510017
The AIDS Myth at 30
Erhard Geissler
Article Type: Short Review | First Published: March 03, 2016
In 1985 the KGB and East Berlin's professor of Biology started the AIDS disinformation campaign by accusing the United States of America of having constructed and spread the AIDS agent in the course of biological weapons research. Now, 30 years later, a German authority, The Federal Commissioner for the Records of former East Germany's State Security Service, the "Stasi", is spreading disinformation regarding the alleged substantial involvement of Stasi officers in the campaign....
Open Access DOI:10.23937/2469-567X/1510015
Organotropic Kinetics in Acute Sublethal Transient Cytomegalovirus Infection in Mice
Daniel Benharroch, Ory Rouvio, Aharon Palmon and Bracha Rager
Article Type: Research Article | First Published: January 03, 2016
Murine cytomegalovirus (MCMV) shows many similarities with the human virus (HCMV). This is a ubiquitous DNA virus from the betaherpesvirus group. A self-limiting acute phase of viral infection and a persistent latent phase normally characterize the pathogenesis of MCMV infection in the immunocompetent host. The MCMV widespread distribution occurs via the blood and its mononuclear cells. In the more common congenital viral infection, the HCMV causes birth defects, including mal-development of the...
