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International Journal of

Stem Cell Research & TherapyISSN: 2469-570X

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 Open Access DOI:10.23937/2469-570X/1410009

Dental Stem Cells Characterization and Bone Regenerative Potential in Oral Medicine

Ricardo Rodrigues, Barbara Viana, Ivo Vieira, Joao Tavares, Renato Lobo, Ana Portela and Mario Vasconcelos

Article Type: Review Article | First Published: June 02, 2015

The oral cavity has proven to be an important reservoir of stem cells with the advantage of being a non-invasive source. These cells potential for maxillo-facial bone regeneration has been well documented throughout the last five years. This article aims at reviewing and discussing the different types of dental stem cells available in the oral cavity, their lineage characterization and potential applications in oral medicine; cell collection, isolation and preservation; bone regenerative potenti...

 Open Access DOI:10.23937/2469-570X/1410008

The Decision for Regenerative Endodontic Therapy

Anastasia Agrafioti, Maria Deimezi and Evangelos G. Kontakiotis

Article Type: Review Article | First Published: April 19, 2015

Regenerative endodontics is described as biologically based procedures designed to replace damaged structures, including dentin and root structures, as well as cells of the pulp-dentin complex, and is considered as an optimal approach for treating the immature permanent tooth with a necrotic pulp....

 Open Access DOI:10.23937/2469-570X/1410007

Enhancement of Human Adipose-Derived Stem Cell Expansion and Stability for Clinical use

Swenn Maxence Krähenbuhl, Anthony Grognuz, Murielle Michetti, Wassim Raffoul and Lee Ann Applegate

Article Type: Research Article | First Published: April 06, 2015

Co-culture techniques associating both dermal firoblasts and epidermal keratinocytes have shown to have better clinical outcome than keratinocyte culture alone for the treatment of severe burns. Since fat grafting has been shown to improve scar remodelling, new techniques such as cell-therapy-assisted surgical reconstruction with isolated and expanded autologous adipose-derived stem cells (ASCs) would be of benefit to increase graft acceptation....

 Open Access DOI:10.23937/2469-570X/1410006

Mechanical Loading Promoted Discogenic Differentiation of Human Mesenchymal Stem Cells Incorporated in 3D-PEG Scaffolds with rhGDF5 and RGD

S. Guggisberg, L. M. Benneker, M. J. Keel and B. Gantenbein

Article Type: Research Article | First Published: March 28, 2015

Synthesized polyethyleneglycol (PEG) hydrogels are appealing with regard to potential for cell therapy or as vehicles for drug delivery or even to regenerate tissue with similar hydrogel-like properties such as the nucleus pulposus of the intervertebral disc (IVD)....

 Open Access DOI:10.23937/2469-570X/1410005

Comparative Characterization of Canine and Human Mesenchymal Stem Cells Derived from Bone Marrow

Bertolo A, Schlaefli P, Malonzo-Marty C, Baur M, Potzel T, Steffen F and Stoyanov J

Article Type: Research Article | First Published: January 19, 2015

Bone marrow is a major source of Mesenchymal Stem Cells (MSC), which are used in tissue engineering and other autologous stem cell therapies. Studies designed to use large canine models and translate the results to human practice must take into account the ex vivo and in vitro differences in the bone marrow samples. A set of morphological and physiological markers was used to compare MSC derived from canine and human bone marrow. Despite anticlotting treatment, frequent bone marrow clotting was ...

Volume 2
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