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Original Article  |   Volume 3, Issue 2

Objective Quantitative CT Evaluation using Different Attenuation Ranges in Patients with Pulmonary Fibrosis: Correlations with Visual Scores

Shin Matsuoka, Tsuneo Yamashiro, Shoichiro Matsushita, Atsuko Fujikawa, Kunihiro Yagihashi and Yasuo Nakajima
Abstract

Objective quantitative evaluation for the extent of fibrosis has been introduced using CT densitometry in patients with interstitial lung diseases, however, there have been no definitive attenuation cut-off values to evaluate the extent of ground-glass opacity and fibrosis separately. This study was conducted to investigate the relationships between quantitative CT measurements using different attenuation ranges and visual CT scores, and to determine whether the different attenuation ranges can estimate the extent of ground-glass opacity and fibrosis separately in patients with pulmonary fibrosis.

  PDF   |    Full Text | DOI: 10.23937/2378-3516/1410049

Original Research Article  |   Volume 3, Issue 2

Prevalence of Chronic Obstructive Pulmonary Disease in Southwestern Taiwan: A Population-Based Study

Su-Lun Hwang, Yu-Ching Lin, Su-Er Guo, Miao-Ching Chi, Chiang-Ting Chou and Chieh-Mo Lin
Abstract

Objective: Chronic obstructive pulmonary disease (COPD) poses a substantial burden of illness in the Asia-Pacific region, as it does worldwide. However large-scale and community-based epidemiology studies of COPD in Taiwan are limited. This paper conducted a population-based study to investigate the prevalence of COPD in southwestern Taiwan. Methods: Data were conducted using a subset of medical claims data from the National Health Insurance Research database (NHIRD) from 2008 to 2010. The prevalence of COPD was calculated for the population aged 40 years and older in southwestern Taiwan. The relative risks (RRs) of prevalence for COPD was estimated using a multiple linear regression model.

  PDF   |    Full Text | DOI: 10.23937/2378-3516/1410048

Original Research Article  |   Volume 3, Issue 2

Outcome Predictors of Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Role of Inflammatory Biomarkers

Hanaa Shafiek, Nashwa Abd-elwahab, Manal Baddour, Akram Degady, Mohamed El-hoffy and Yehia Khalil
Abstract

Objective: To assess the value of interleukin-6 (IL-6), interleukin-8 (IL-8) and C-reactive protein (CRP) in predicting the outcome of acute respiratory failure (ARF) on top of COPD. Patients and methods: Serum samples were collected from 33 COPD patients presented with ARF for IL-6, IL-8, and CRP analysis on admission, after 72 hours and after 14 days. Sputum samples were taken for microbiological evaluation.

  PDF   |    Full Text | DOI: 10.23937/2378-3516/1410047

Case Report  |   Volume 3, Issue 2

Left Hemi-Diaphragmatic Hydatid Cyst - A Rare Presentation and Diagnostic Challenge

Haris Hakeem, Ghulam Fareed, Muhammad Irfan and Saulat Fatmi
Abstract

Echinococcosis or hydatid cyst disease is among the oldest diseases known to man. Common presentations include involvement of liver and lungs. Hydatid cyst in diaphragm without hepatic involvement is rare and less than 100 cases are reported in literature. We are describing a case of a young female who presented with cough anddyspnea secondary to large cysts that appeared to involve the right lung and spleen on initial imaging studies. Peroperatively, however, the presumed spleenic cystwas surprisingly found to be lying within left hemidiaphragm. Complete surgical resection of the cysts was performed with uneventful post-operative recovery.

  PDF   |    Full Text | DOI: 10.23937/2378-3516/1410046

Case Report  |   Volume 3, Issue 2

A Case Report: What is the Real Cause of Death from Acute Chlorine Exposure in an Asthmatic Patient?

Toprak S and Kalkan EA
Abstract

This case report presents an acute and chronic inflammation process at the same time and resulted in death following exposure to chlorine gas. A 65-years-old woman died shortly after cleaning her bathroom with a mixture of various chemicals including bleach and an acid containing product. She was declared dead when she arrives to hospital. She is a non-smoker and has no significant medical history other than asthma. Toxicological analysis showed that paracetamol, methylprednisolone, venlafaxine and its metabolite O-desmethylvenlafaxine were detected in blood.

  PDF   |    Full Text | DOI: 10.23937/2378-3516/1410045

Original Research  |   Volume 3, Issue 2

Prevalence of Depression/Anxiety among Medicare Beneficiaries with Chronic Obstructive Pulmonary Disease and Association with Acute Exacerbations

Christopher M. Blanchette, Melissa Roberts, Hans Petersen and Anne Fuhlbrigge
Abstract

A prevalent cohort of Medicare beneficiaries aged 65+ with COPD (chronic bronchitis, emphysema, bronchiectasis, chronic airway obstruction) was constructed from a 5% sample of Medicare beneficiaries. Existence of depression/anxiety was identified via healthcare services or prescription drug claims. Baseline characteristics were assessed (1/1/2006-6/31/2006) and patients followed from first depression/anxiety claim until 12/31/2007 for all-cause and respiratory-related healthcare cost and utilization. Prevalence estimates of co-occurring COPD and depression/anxiety were approximated.

  PDF   |    Full Text | DOI: 10.23937/2378-3516/1410044