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International Journal of

Ophthalmology and Clinical ResearchISSN: 2378-346X

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 Open Access DOI:10.23937/2378-346X/1410045

Is Balancing Blood Pressure Night Dips Effective in Preventing Glaucoma Progression? A Pilot Study

Gil Peretz and Miriam Zalish

Article Type: Research Article | First Published: December 24, 2015

Much has been written about the relationship between intraocular pressure (IOP) and glaucoma. An elevated IOP has been found to be a risk factor for both glaucoma development and progression, and IOP reduction has been useful in at least slowing disease progression [1-4]. Some glaucoma patients continue to progress in spite of having low IOP levels, and this applies to treated patients with primary open angle glaucoma (POAG) as well as treated patients with normal tension glaucoma (NTG)....

 Open Access DOI:10.23937/2378-346X/1410044

Lutein and Zeaxanthin Isomers Inhibits Cholinesterase and Modulates the Expression of Inflammation-Related Genes: In Vitro Models

Khadija Ghanam, Jayant Deshpande and Vijaya Juturu

Article Type: Research Article | First Published: December 16, 2015

It is well established that ultraviolet (UV) radiation induces immunomodulatory effects involved in different chronic conditions including skin cancer, age-related macular degeneration (AMD), refractive errors, glaucoma and cataracts. Epidemiological studies suggest solar radiation is responsible for some of the deteriorating changes that lead to AMD Recent studies have shown that UVA (320-400 nm) and UVB (290-320 nm) radiation are immunosuppressive. Experimental studies have demonstrated that b...

 Open Access DOI:10.23937/2378-346X/1410043

Clinical Evidence of Ambient Temperature Variations on Femtosecond Laser Performance and Comparison with a Mechanical Microkeratome

Bojan Pajic, Brigitte Pajic-Eggspuehler, Iraklis Vastardis, Michael Mrochen and Zeljka Cvejic

Article Type: Research Article | First Published: December 15, 2015

The mechanism of flap creation with the IntraLase femtosecond laser has already been described extensively in the literature over the years. Femtosecond laser systems produce energy pulses (600 to 800 femtosecond) at an infrared wavelength of 1053 nm. The ultra-short impulses are focused at a spot size of a few micrometers in diameter at a preset depth within the stroma, leading to photo disruption and to a creation of a corneal resection plane. Once the flap has been created, the device creates...

 Open Access DOI:10.23937/2378-346X/1410042

New Diagnostic Criteria for Infantile Nystagmus. An Upgraded Nystagmus Clinical Approach

Nadim Nasser

Article Type: Original Article | First Published: November 26, 2015

Purpose: CEMAS group has classified nystagmus comprehensively in 2001. From that time, several attempts to make the subject as uniform as possible, needed continuous upgrading. This manuscript is an upgraded clinical approach for diagnosis of Irreversible Congenital Nystagmus, which is in addition to its being one of the major clinical features of intrinsic ocular diseases, is also a sign of inborn errors of myelination. Design: We will accompany the way to the diagnosis of congenital irreversib...

 Open Access DOI:10.23937/2378-346X/1410041

Intravitreal Implant of Dexamethasone for Treatment of Refractory Cystoid Macular Edema Surgically Induced After Pars Plana Vitrectomy

Rino Frisina and Barbara Parolini

Article Type: Research Article | First Published: November 02, 2015

Purpose: To evaluate the efficacy and safety of intravitreal implant of Dexamethasone (Ozurdex, Allergan, Irvine, Calif, USA) for the treatment of refractory and chronic cystoid macular edema secondary to PPV and peeling of ERM and internal limiting membrane (ILM) with or without simultaneous cataract surgery. Methods: Seven eyes of 7 patients affected by chronic and refractory CME for at least 3 months after vitrectomy and peeling of ERM and ILM, were recruited. All patients underwent intravitr...

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