Central nervous system CNS toxicity is a rare complication of a commonly used antibiotic, metronidazole. We report a representative case of metronidazole-induced encephalopathy in an individual with increased vulnerability due to underlying liver disease. Features included the essential clinical symptoms of dysarthria and ataxia and characteristic MR abnormalities of increased T2 and FLAIR signal in the dentate nuclei both of which were rapidly reversible upon drug discontinuation....

We reported one case of congenital skull depression in a male newborn who delivered by cesarean section due to continued occipitotransverse position. His mother had no history of abdominal trauma during the pregnancy, and there were no complications and difficulties in the process of cesarean delivery. The neurological examination of the baby was normal after birth. The depression had completely resolved when the child was 4 months. The child was meeting all appropriate developmental milestones ...

Synapse remodeling is an essential physiological phenomenon in maintaining the normal brain function. Traumatic injury is one of the causes that triggers abnormality in synapse remodeling, leading to neurodegeneration. So far, substantial clinical trials have been attempted to cure neurodegeneration. One of the challenging approaches that improves neurodegenerative symptoms is therapeutic hypothermia. The putative positive feature induced by therapeutic hypothermia on patient is neuroprotection;...

The utility of endoscopic biopsy using high-dose fluorescein sodium in biopsy of malignant brain tumors was investigated. The subjects were 9 patients with malignant brain tumors (malignant lymphoma 5, glioblastoma 3, metastatic brain tumor 1). After making an incision in the dura mater, 20 mg/kg fluorescein sodium were administered intravenously. A transparent sheath was then inserted under neuronavigation guidance. To observe the tumor, an endoscopic biopsy was performed using normal white lig...