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Dermatology Research and TherapyISSN: 2469-5750

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 Open Access DOI:10.23937/2469-5750/1510076

The Role of the CD57+ T-Lymphocytes in Various Malignancies and Their Potential Contribution to the Increased Frequency and Aggressiveness of Cscc in OTR

Shaikah Al-Aojan

Article Type: Mini Review | First Published: December 30, 2019

Organ transplant recipients (OTR) have 100-fold increased risk for cutaneous squamous cell carcinoma (cSCC) compared to the general population. Modified immune surveillance mechanisms may contribute to the perceived differences in incidence, clinical behavior and increased aggressiveness of cSCC in OTR. It could also provide some insight into the pathogenesis of cSCC in various disorders characterized by low immunity such as HIV, hematological malignancies and immune-mediated inflammatory disord...

 Open Access DOI:10.23937/2469-5750/1510075

A New Way to Inhibit IL-17 in Psoriasis: Real-Life Use of Brodalumab Goes Beyond Clinical Trials Expectations

Mario Valenti, Paola Facheris, Giulia Pavia, Alessandra Narcisi, Riccardo Borroni and Antonio Costanzo

Article Type: CASE SERIES | First Published: December 30, 2019

Psoriasis is a common inflammatory skin disease that is estimated to affect about 2-4% of the population, with rates varying across ethnic groups and geographical regions. Biotechnological (more commonly called biologic drugs) drugs have shown great results in treating severe forms of psoriasis. Biologic agents that specifically block the IL-17 pathway have shown promising results with regard to efficacy and safety. Specific IL-17 inhibitors are represented by Secukinumab and Ixekizumab, fully h...

 Open Access DOI:10.23937/2469-5750/1510074

Psychosocial Impact of Rosacea on Women

Mohammed Al Abadie, Farlin Asharaff and Dina Al Abadie

Article Type: Research Article | First Published: September 09, 2019

Rosacea is found in approximately 10% of the general population and is known to mainly affect people from 30 to 60 years of age. It is more prevalent in female population as opposed to male population (with the exception of phymatous rosacea where majority of affected patients are adult male). A 2012 study consisting of 60,042 patients in the United Kingdom identified that 61.5% of patients with rosacea was female. Further studies suggest that rosacea has a greater impact on quality of life of f...

 Open Access DOI:10.23937/2469-5750/1510073

Hyperchromic and Erythematous Pityriasis: Case Report and Review of the Literature

Medina Andrade Luis Angel, MD, Laura Guadalupe Medina Andrade, MD, Lizbeth Elisa Oropeza Lopez, MD, Andrea Marianne Rodriguez Valencia, MD, Haizel Valencia Romero, MD, Angel Adrian Moreno Pina, MD, Araceli Esteban Chaparro, MD, and Alberto Robles Mendez Hernandez, MD

Article Type: Review Article | First Published: July 31, 2019

Pityriasis versicolor is a superficial fungal infection of the skin, characterized by pigmentary changes secondary to the colonization of the stratum corneum by a lipophilic dimorphic fungus known as Malassezia sp. Of this genus, 7 species known as the causative agent of pityriasis versicolor, the most frequently isolated species is M. Globosa. This skin disease occurs worldwide but predominates in the tropical, warm, and humid climate. Malassezia sp classified as dimorphic fungi since it behave...

Volume 5
Issue 2