Journal of

Dermatology Research and TherapyISSN: 2469-5750


 Open Access DOI:10.23937/2469-5750/1510072

Lupus Miliaris Disseminatus Faciei Treated By Isotretinoin and Platelet Rich Plasma

A Lahrichi, F Hali, K Baline, F Marnissi and S Chiheb

Article Type: Case Report | First Published: May 17, 2019

An 18-year-old patient presented with lupoid papulonodular lesions in the face. The diagnosis of disseminated lupus of the face was retained after eliminating other diagnoses including sarcoidosis, syphilis and leprosy. An antibacillary treatment was started without improvement for 3 months with onset of lesions. A 0.5 mg/kg/day isotretinoin treatment was started with improvement of the lesions. Thereafter, the patient benefited from 6 sessions of injection of platelet-rich plasma (PRP) with sag...

 Open Access DOI:10.23937/2469-5750/1510071

Axillary Fox-Fordyce Disease Induced By Laser Hair Removal

Robustelli Test Elisa, Ferreli Caterina, Brundu Maria Angela, Atzori Laura, Pilloni Luca and Rongioletti Franco

Article Type: Case Report | First Published: May 15, 2019

Fox-Fordyce disease (FFD) is an uncommon chronic inflammatory skin disease of the apocrine sweat glands that could be considered as a rare adverse event of laser hair removal. It is postulated that laser therapy could induce damage to the follicular infundibulum, resulting in epidermal detachment and altered keratinocytes maturation which led to keratin plugging. Here, we present a case of a post-pubertal woman who developed axillary itchy lesions with clinical and histological features compatib...

 Open Access DOI:10.23937/2469-5750/1510070

Approaches to the Potential Use of Stromal Vascular Fraction and Coenzyme Q10 in Dermatological Aesthetics: A Systematic Review

Isabela de Lima Bocalon, Mayara Fernandes Veri Marques and Idiberto Jose Zotarelli Filho

Article Type: Research article | First Published: May 08, 2019

With aging, occurs a decrease in the number of melanocytes active enzymatically around 12.0% to 24.0% every ten years. As a treatment, stem cell therapy with adult stem cells has been the focus of many studies. Among adult stem cells, adipose-derived stem cells (ADSC) ubiquinone, known as coenzyme Q10 (CoQ10), is a lipid-soluble antioxidant. It is shown to reduce lipid peroxidation of low-density lipoprotein regenerates endogenous vitamin E and protects cells against oxidative stress induced by ...

 Open Access DOI:10.23937/2469-5750/1510069

Dermatologic Manifestations in Patients on Chronic Hemodialysis

Ahmed Bouhamidi, Mohamed El Amraoui, Hicham Rafik, Mohammed Boui and Naoufal Hjira

Article Type: Research article | First Published: April 27, 2019

Dermatological manifestations are frequent and varied among chronic hemodialysis patients. The aim of this study is to determine the prevalence and characteristics of cutaneous abnormalities observed in hemodialysis patients. We led a transversal study, conducted at the Nephrology Department of the 5th Military Hospital in Guelmim, from March to May 2017, including 44 hemodialysis patients....

 Open Access DOI:10.23937/2469-5750/1510068

Remission of Psoriasis during Treatment with Apatinib in a Patient with Rectal Cancer

Daoqun Chong, Gai Ge, Dongmei Li, Yang Yang, Rong Wang, and Dongmei Shi, MD, PhD

Article Type: CASE REPORT | First Published: March 14, 2019

Psoriasis is a chronic, recurrent inflammatory skin disease characterized by abnormal keratinocyte proliferation and vascular hyperplasia. Apatinib is a tyrosine kinase inhibitor which has been reported to be effective in some tumors thought to be associated with inhibition of the proliferation of endothelial cells by selectively inhibiting vascular endothelial growth factor receptor-2 (VEGFR-2). We present a 54-year-old patient with a 30-year history of psoriasis, who did not respond well to or...

 Open Access DOI:10.23937/2469-5750/1510067

Use of Vibrational Optical Coherence Tomography to Image and Characterize a Squamous Cell Carcinoma

Frederick H Silver, Ruchit G Shah, Michael Richard and Dominick Benedetto

Article Type: ORIGINAL ARTICLE | First Published: March 08, 2019

Previous literature reports suggest that tissue stiffness is a predictor of cancer and metastatic behavior. We have used optical coherence tomography and vibrational analysis (VOCT) to characterize normal skin, scar and a verrucous carcinoma, a squamous cell carcinoma subtype, non-invasively and non-destructively. The results suggest that epidermal thickening and increased keratin production occur in verrucous carcinoma and lead to increases in surface hills and valleys as well as subsequent inc...

 Open Access DOI:10.23937/2469-5750/1510066

Management of Cutaneous Toxicity Secondary to Targeted Agents in Melanoma

Maria del Carmen Pantin Gonzalez, Diego Malon Gimenez, Beatriz Losada Vila, Beatriz Anton Pascual, David Gutierrez Abad, Nadia Sanchez Banos and Cristina Sanchez Cendra

Article Type: CASE REPORT | First Published: February 28, 2019

Melanoma is the most aggressive skin cancer and its incidence continues to increase worldwide. Molecular targeted kinase inhibitors have improved survival and tumor response for those patients with BRAF mutant disease. We describe the case of a patient under treatment with BRAF and MEK inhibitors (BRAFi and MEKi) who presents cutaneous toxicity grade 3, as an adverse effect due to treatment....

 Open Access DOI:10.23937/2469-5750/1510065

Nail Disorders in Patients with Chronic Renal Failure

Niema Aqil, Aicha Nassiri, Salim Gallouj and Fatima Zahra Mernissi

Article Type: Original Article | First Published: January 28, 2019

Ungual manifestations occurring in patients with end stage renal failure are polymorphic and diverse. The aim of our study was to assess the prevalence and characteristics of different ungual manifestations in patients end stage renal failure. We led a transverse investigation of all patients with end stage renal failure followed in the department of nephrology of University Hospital Hassan II, during a period of three months from 01 August 2016 to 01 November 2016....

 Open Access DOI:10.23937/2469-5750/1510064

Case of Th2 Cytokines in a Japanese Girl Who Acquired Hookworm-Related Cutaneous Larva

Makoto Kondo and Keiichi Yamanaka

Article Type: Case Report | First Published: January 11, 2019

One of the symptoms of creeping disease in humans is the accidental occurrence of hookworm-related cutaneous larva migrans (HrCLM). It usually occurs following contact with soil, sand, and mud found on beaches in tropical countries. Skin eruptions, such as linear nodules, appear on the foot and lower extremities. Misdiagnosis and inefficient treatment for travelers have often been reported. Although the parasite species remained unidentified in our case, the characteristic skin eruption in combi...

 Open Access DOI:10.23937/2469-5750/1510063

Dermoscopic Features of Linear Porokeratosis: Different Aspects in its Development

Meltem Turkmen, Bengu Gerceker Turk, Isıl Kilinc Karaarslan, Gulsen Kandiloglu and Fezal Ozdemir

Article Type: Original Article | First Published: January 10, 2019

A 22-year-old-woman admitted with linear brownish papules and plaques on the right side of the trunk. The lesions initially had appeared on the right mammary at the age of 2-months and disseminated regionally throughout the axilla. The patient was previously followed with the diagnosis of epidermal nevus by some other physicians. On dermatologic examination, red-brown hyperkeratotic linear and annular plaques with elevated borders extending from the right mammary to the right axilla along the Bl...

Volume 5
Issue 1