Topical Treatment of Cutaneous Leishmaniasis: Wound Reduction in Mice Using N-Methyl Glucamine from PVP and Nano Clay Membranes
Maria Jose Alves de Oliveira, Regina Maia, Lucia Almeida Braz, Ademar Benevolo Lugao, Valdir Sabbaga Amato and Duclerc Fernandes Parra
Article Type: Original Article | First Published: October 24, 2016
Biomaterials comprise a scientific field where synthetic materials are developed for pertinent biological functions, yielding a wide diversity of new products. Although widely employed, they still require improvement for therapeutic purposes. The objective of this study was to develop poly (N-2-vinyl-pyrrolidone) (PVP), poly (vinyl alcohol) (PVAl), clay, and N-methyl glucamine hydrogels for the treatment of cutaneous leishmaniasis. The characterization techniques used were tumescence, energy-dis...
The Role of the Mast Cell in Skin Aging
Yang-lin Hua, Wei Gao, Hong-ying Li and Jian Tang
Article Type: Mini Review | First Published: October 14, 2016
Skin is the external organ of human body that provides protection against environmental stress. Direct and indirect damage causes skin aging. Scientists have been struggling to explore the mechanisms of skin aging and to think of ways to delay this course. The role of mast cell in regulating skin aging has attracted much attention recently. The granules of mast cell contain a great diversity of highly toxic compounds and active mediators. Degranulation of mast cell in papillary dermis may lead t...
Cutaneous Manifestations in Patients with Systemic Lupus Erythematosus: Data from a Multiethnic Latin American Cohort (GLADEL)
Maria J Haye Salinas, Veronica Saurit, Alejandro Alvarellos, Francisco Caeiro, Daniel Wojdyla, Cristina Drenkard, Guillermo J Pons-Estel, Luis J Catoggio, Judith Sarano, Eduardo Ferreira Borba, Emilia Sato, Sergio Jacobelli, Luis A Ramirez, Marlene Guibert -Toledano, Virginia Pascual-Ramos, Mario H Cardiel, Maria I Segami, Isaac Abadi, Graciela S Alarcon, Bernardo A Pons-Estel and Latin American Study Group on Lupus (GLADEL)
Article Type: Original Research | First Published: October 12, 2016
SLE patients from 34 centers in nine Latin American countries with a recent diagnosis (≤ 2 years) were studied. Socioeconomic-demographic characteristics and clinical features according to the presence of cutaneous manifestations were examined by univariable and multivariable logistic regression analyses. Their predictive value for the occurrence of other clinical manifestations was also examined....
A Fatal Infection due to Gordonia Terrae
Jeong Rae Yoo, Miyeon Kim, Keun Hwa Lee, Seung Jin Yoo, Chang lim Hyun, Jonghwan Bae, Sang Taek Heo and Yong-Geun Park
Article Type: Case Report | First Published: October 05, 2016
A 53-year-old man with a history of poliomyelitis underwent left total hip arthroplasty in December 2011. His past medical history was not significant except the medical conditions described disease. The patient had developed a sore on right perianal area since March 2013 (Figure 1A), and infected sore lesion was extended to abscess on a right buttock abscess one year later, it was managed with incision and drainage in right buttock abscess since November 2014. ...