International Journal of

Diabetes and Clinical ResearchISSN: 2377-3634

Archive

 Open Access DOI:10.23937/2377-3634/1410098

Insulin Acts as Stimulatory Agent in Diabetes-Related Escherichia Coli Pathogenesis

amelija Madacki-Todorovic, Izet Eminovic, Nadira Ibrisimovic Mehmedinovic and Mirza Ibrisimovic

Article Type: Research Article | First Published: December 05, 2018

In general, diabetic patients are more prone to microbial infections, which is believed to be caused due to high glucose levels in blood which compromise components of the immune system. However, it is little known about role of therapeutic insulin administration on dissemination of infectious diseases in people with diabetes mellitus. The study included the clinically isolated strains of Escherichia coli (E. coli) with biofilm forming capacity as well as referent non-biofilm former E. coli stra...

 Open Access DOI:10.23937/2377-3634/1410097

Incidence of Urinary Tract Infections and Allergic Conditions among Type 2 Diabetes Mellitus Patients in Rural Hospital Clinics in Sri Lanka

JGA Sachinthana, GM Kariyawasam, EMDT Edirisinghe, HSN Peiris, DARK Dayara-thna, FM Mowlana and JMKB Jayasekara

Article Type: Research Article | First Published: November 07, 2018

Urinary tract infections (UTI) and allergic conditions in individuals with diabetes mellitus (DM) may evolve to serious complications unless managed properly. Early diagnosis and evaluation of these conditions of DM pa-tients are important to maintain the quality of life of the patients. The objective of the current study was to identify the incidence of UTIs among type 2 DM patients....

 Open Access DOI:10.23937/2377-3634/1410096

Insulin Resistance Modification is a Game Changer for Type 2 Diabetes Treatment Strategy

Juraj Gmitrov

Article Type: Review Article | First Published: October 15, 2018

Insulin resistance, appearing years before diabetes main diagnostic sign, hyperglycemia, stands in the origin of type 2 diabetes (T2DM), generated by complex impairment of a spectrum biochemical processes the most important of which is the failure of phosphatidylinositol 3-kinase enzymatic chain responsible for glucose uptake and endothelial nitric oxide (NO) synthase activation. Therefore in conditions with insulin resistance the impairment of glucose uptake is strongly coupled with NO deficit ...

 Open Access DOI:10.23937/2377-3634/1410095

Zinc Supplementation Attenuated Calcium-High Diet Effect on Zinc Status and Carbohydrate Metabolism of Non-Diabetic and Diabetic Rats

Samir Derouiche and Zine Kechrid

Article Type: Original Article | First Published: October 03, 2018

The bioavailability of zinc can be influenced by several dietary factors, among them calcium level, which leads to zinc metabolism disturbance. Thus, the present study was under taken to evaluate the effect of zinc supplementation on zinc status and carbohydrate metabolism in non-diabetic and diabetic rats fed high-calcium diet. Diabetes is a group of metabolic disorders characterized by chronic hyperglycemia resulting from disorders of secretion or the action of insulin. This hyperglycemia is a...

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