International Journal of

Cancer and Clinical ResearchISSN: 2378-3419


 Open Access DOI:10.23937/2378-3419/1410161

Proposed Immunology of the Spontaneous Remission of Leukemia

Behzad Niakan

Article Type: Research Article | First Published: October 29, 2021

Spontaneous remission of leukemia is more likely to occur after anti-biotic treatment of an infection, termination of pregnancy, blood transfusion and host versus graft reaction. All have in common a drop in platelet count followed by a rise in platelet count. Spontaneous remissions of leukemia may be preceded by a low platelet count, anemia or low hemoglobulin. Also, once spontaneous remission of leukemia occurs there may be a simultaneous rise in platelet count and hemoglobulin. The drop and r...

 Open Access DOI:10.23937/2378-3419/1410160

A Novel Transcriptional Score Predicting the Benefit of Anti- EGFR Antibodies for RAS Wild-Type Metastatic Colorectal Cancer: An In Silico Study

Huan Huang, He Xiao, Qin Zhang, Jian Li, Yunfei Ye, Rong He and Xueqin Yang

Article Type: Research Article | First Published: October 08, 2021

There is still an urgent need for precise biomarkers for predicting the clinical outcome of anti-EGFR antibody treatment for metastatic colorectal cancer. We hypothesized that transcriptome signatures might act as a more effective biomarker beyond RAS mutations and anatomic sites. This study was undertaken to develop a transcriptional score predictive of benefit of anti-EGFR antibodies for RAS wild-type metastatic colorectal cancer. The Gene Expression Omnibus (GEO) dataset GSE5851 was used to d...

 Open Access DOI:10.23937/2378-3419/1410159

Total Maxillectomy in Children: A Report Two Cases

Agustina Lorea, Eduardo Figueroa, Juan LarraƱaga and Carlos S Ruggeri

Article Type: Case Report | First Published: September 08, 2021

We describe the clinical cases of two pediatric patients who were treated with a total maxillectomy and chemo/ radiotherapy for suffering from malignant tumors of the maxilla. The reconstruction of the floor of the orbit was done with titanium micromesh and the defect in the maxilla and hard palate was reconstructed with free flaps. This allowed a quick swallowing rehabilitation and an excellent cosmetic result. Total maxillectomy is a surgical technique that involves the resection of all the bo...

 Open Access DOI:10.23937/2378-3419/1410158

Proposed Biology of the Spontaneous Remission of Cancer

Behzad Niakan

Article Type: Hypotheses | First Published: September 08, 2021

Two common factors were identified among the case reports of the prolonged spontaneous remission and regression of cancer. The prolonged spontaneous remissions of cancer may be preceded by a low blood oxygen delivery to the tumor and a short, steady or rapid malignant growth. The steady or rapid growth of primary tumor not the growth of new metastases. Case reports of the spontaneous disappearance of verified cancer without any medical intervention has baffled researcher. The disappearance of al...

Volume 8
Issue 5