Carlos S Ruggeri, Eduardo Figueroa, Agustina Lorea, Gabriel Rondón Gonzalez and Ana Carolina Riveros
Article Type: Original Article | First Published: June 30, 2021
Eight patients had melanomas, five located in the paranasal sinuses, two in the nasal cavity and one in nasal cavity and maxillary sinus. The incidence of melanomas in our population of patients with rhinosinusal malignant tumors was 11.11%. Three patients were treated with surgery and radiotherapy and three with surgery only. Two were treated with palliative criteria. In the six patients treated with curative intent, the local control and specific survival were 83.33%, and 66.66% respectively. ...
Dietary Heterocyclic Amine Intake and Risk of Esophageal Squamous Cell Carcinoma in Rural Uganda
Samson OKELLO, Emmanuel BYARUHANGA, Suzan Joan AKELLO, Emmanuel DWOMOH, Christopher Kenneth OPIO, Kathleen E. COREY, Ponsiano OCAMA, Jingshu GUO, Winnie R. MUYINDIKE, Robert J. TURESKY and David C. CHRISTIANI
Article Type: Research Article | First Published: June 30, 2021
Dietary exposure to 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) in cooked meats maybe responsible for the high burden of Esophageal squamous cell carcinoma (ESCC) in southwestern Uganda. We conducted a pilot case-control study among 31 histologically confirmed ESCC cases and 54 age, gender, and residence matched healthy community controls sampled from the general population at the time of accrual of each case in southwestern Uganda. We collected data including smoking, alcohol consu...
Assessment of Pivka II as Tumour Marker in Hepatocellular Carcinoma
Anuj Parkash, Parul Singla and Ashok Kumar Ahirwar
Article Type: Research Article | First Published: May 10, 2021
The most commonly used tumor marker in hepatocellular carcinoma (HCC) is serum alpha-fetoprotein (AFP). It has been routinely used for monitoring the prognosis of disease, but not for its detection. There is always a quest of new biomarkers for detection of HCC. The present study has been designed to determine the level of prothrombin induced by vitamin K absence-II (PIVKA II) in sera of patients suffering from HCC. The aim of this study is to evaluate the PIVKA II as a biomarker for HCC indepen...