The Management of Mucositis of Pediatric Hematopoietic Stem-Cell Transplantation
CIFTCIOGLU Sule and EFE Emine
Article Type: Perspective | First Published: September 23, 2015
Hematopoietic stem-cell transplantation (HSCT) is used primarily for hematologic and lymphoid cancers but also for many other disorders. Autologous HSCT (in which stem cells are derived from the patient) is mainly used to treat chemosensitive malignancies. Allogeneic HSCT (in which the stem cells are derived from a donor) is often the preferred treatment option, particularly in patients with acute leukaemia. Oral complications are a significant cause of morbidity and potential mortality for chil...
The Levels of PAI-1, Urokinase uPA, Thrombomodulin and TFPI in Essential Thrombocythemia
Oktay Bilgir, Ferda Bilgir, Mehmet Calan and Giray Bozkaya
Article Type: Research Article | First Published: September 05, 2015
Generally, ET is a myeloproliferative disorder characterized by persistent peripheral thrombocytosis and abnormal megakaryocytic proliferation in the bone marrow. ET is a rare cause of thrombocytosis and may be associated with both venous and arterial thrombosis in 10-75% of cases, depending largely on the study and whether vasomotor symptoms are included in thrombotic manifestations....
The Role of Positron Emission Tomography Imaging in the Risk-Adapted Treatment of Stage I-II Hodgkin's Lymphoma - A Retrospective Analysis
Tom Rider, John Jones, John Brewin, Gillian Horne, Jack Wills, Hannah Barton, Kevin Boyd, Timothy Corbett, Sabina Dizdarevic and Timothy Chevassut
Article Type: Research Article | First Published: July 09, 2015
Early stage Hodgkin's Lymphoma (HL) has excellent outcomes and recent research has focused on minimising treatment-related toxicities. However, the role of 18F-florodeoxyglucose positron emission tomography (FDG PET) imaging in this setting is not fully determined. We retrospectively calculated overall survival (OS) and relapse free survival (RFS) in stage I-II HL when radiotherapy was omitted if post-chemotherapy FDG PET imaging was negative....