Importance of Prostate-Specific Antigen Screening before and after Bacillus Calmette-Guerin Intravesical Bladder Instillation Treatment to Avoid Unnecessary Prostate Biopsy
Takehiko Okamura, Hidetoshi Akita, Kenji Yamada, Takahiro Kobayashi, Ryosuke Ando, Noriyasu Kawai, Keiichi Tozawa and Takahiro Yasui
Article Type: Research Article | First Published: June 29, 2015
The adverse effects of Bacillus Calmette-Guerin (BCG) intravesical instillation therapy for non-muscle invasive bladder cancer (NMIBC) vary widely, and can include BCG-induced prostatitis. In contrast, prostate cancer may occasionally develop along with bladder cancer. Therefore, if prostate-specific antigen (PSA) levels increase after BCG therapy, a prostate biopsy should be performed to exclude prostate cancer....
A Comparison of Prostatic Acinar Adenocarcinoma Gleason 3+4 versus 4+3 in Different Laboratory Practice Settings
Celia Maria Jesuino Bittencourt, Daniel Abensur Athanazio, Andreia Carvalho dos Santos, Erica Curvelo Dantas Senna, Tania Maria Correia Silva and Luiz Antonio Rodrigues de Freitas
Article Type: Research Article | First Published: March 20, 2015
Objective: To evaluate Gleason 7 tumors from radical prostatectomy specimens that were stratified by 3+4 and 4+3 status, focusing on the clinical and morphologic features. Methods and results: In the first series of 20 Gleason 7 tumors processed by total embedding, cases with 4+3 status were associated with a higher proliferation index. In a second series of 106 Gleason 7 tumors processed by partial embedding, 4+3 status was associated with higher preoperative serum prostate-specific antigen lev...
Male Sling: A Decade Later
Article Type: Editorial | First Published: February 28, 2015
Urethral compression provided by a male sling is not a new concept. A variety of urethral compression procedures have been applied in an attempt to control urinary incontinence over the years. Most notable were the Kaufman procedures which used silicone gel prosthesis to compress the ventral urethra....
Fournier's Gangrene and Prognostic Scoring Systems
Article Type: Editorial | First Published: February 17, 2015
A Fournier's gangrene (FG), a life-threatening necrotizing fasciitis of the male and female genitourinary tract was first described in the 1883. FG is an uncommon necrotizing fasciitis of genitalia and perineum that has high mortality and morbidity. Many predisposing factors have been reported, including perianal disease, urethral stricture, local trauma, diabetes mellitus, and malignancy. Systemic diseases such as cardiac failure, hypertension, and renal insufficiency may have an adverse effect...