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Research Article  |   Volume 1, Issue 1

Importance of Prostate-Specific Antigen Screening before and after Bacillus Calmette-Guerin Intravesical Bladder Instillation Treatment to Avoid Unnecessary Prostate Biopsy

Takehiko Okamura, Hidetoshi Akita, Kenji Yamada, Takahiro Kobayashi, Ryosuke Ando, Noriyasu Kawai, Keiichi Tozawa and Takahiro Yasui
Abstract

The adverse effects of Bacillus Calmette-Guerin (BCG) intravesical instillation therapy for non-muscle invasive bladder cancer (NMIBC) vary widely, and can include BCG-induced prostatitis. In contrast, prostate cancer may occasionally develop along with bladder cancer. Therefore, if prostate-specific antigen (PSA) levels increase after BCG therapy, a prostate biopsy should be performed to exclude prostate cancer.

  PDF   |    Full Text | DOI: 10.23937/2469-5742/1510006

Research Article  |   Volume 1, Issue 1

Repeated Intradetrusor Botulinum Toxin Type A Injections are Still Effective for Patients with Neurogenic Detrusor Overactivity Secondary to Spinal Cord Injury in China

Hui Chen, Xing Hua Yang, Jing Wen Zeng, Ma Ping Huang, Qiu Ling Liu, Jie Bing Huang, Tian Hai Huang, Ke Ji Xi and Chong He Jiang
Abstract

Objective: To assess effective outcomes following repeated treatment with intradetrusor botulinum toxin type an in patients with neurogenic detrusor overactivity (NDO). Methods: Patients with NDO secondary to spinal cord injury (SCI) were enrolled. Botulinum toxin type A 200 U detrusor injections by a rigid cystoscope were repeated.

  PDF   |    Full Text | DOI: 10.23937/2469-5742/1510005

Research Article  |   Volume 1, Issue 1

Outcomes of Two Different Meshes for Treatment of POP with a Concomitant Midurethral Sling for SUI: a Retrospective Cohort Study at 2 Years Postoperatively

Chenghe Wang, Zhong Chen, Guanghui Du, Tao Wang, Weimin Yang and Zhangqun Ye
Abstract

Patients had pelvic organ prolapse (POP) often suffered stress urinary incontinence (SUI) simultaneously. We evaluated the outcomes of two different kits, Prosima and Avaulta pelvic repair systems, with a concomitant midurethral sling by treating the disease and compared the efficacies in a single center.

  PDF   |    Full Text | DOI: 10.23937/2469-5742/1510004

Research Article  |   Volume 1, Issue 1

A Comparison of Prostatic Acinar Adenocarcinoma Gleason 3+4 versus 4+3 in Different Laboratory Practice Settings

Celia Maria Jesuino Bittencourt, Daniel Abensur Athanazio, Andreia Carvalho dos Santos, Erica Curvelo Dantas Senna, Tania Maria Correia Silva and Luiz Antonio Rodrigues de Freitas
Abstract

Objective: To evaluate Gleason 7 tumors from radical prostatectomy specimens that were stratified by 3+4 and 4+3 status, focusing on the clinical and morphologic features. Methods and results: In the first series of 20 Gleason 7 tumors processed by total embedding, cases with 4+3 status were associated with a higher proliferation index. In a second series of 106 Gleason 7 tumors processed by partial embedding, 4+3 status was associated with higher preoperative serum prostate-specific antigen levels and a higher frequency of extraprostatic extension and seminal vesicle invasion.

  PDF   |    Full Text | DOI: 10.23937/2469-5742/1510003

Editorial  |   Volume 1, Issue 1

Male Sling: A Decade Later

Ajay Singla
Abstract

Urethral compression provided by a male sling is not a new concept. A variety of urethral compression procedures have been applied in an attempt to control urinary incontinence over the years. Most notable were the Kaufman procedures which used silicone gel prosthesis to compress the ventral urethra.

  PDF   |    Full Text | DOI: 10.23937/2469-5742/1510002

Editorial  |   Volume 1, Issue 1

Fournier's Gangrene and Prognostic Scoring Systems

Bulent Erol
Abstract

A Fournier's gangrene (FG), a life-threatening necrotizing fasciitis of the male and female genitourinary tract was first described in the 1883. FG is an uncommon necrotizing fasciitis of genitalia and perineum that has high mortality and morbidity. Many predisposing factors have been reported, including perianal disease, urethral stricture, local trauma, diabetes mellitus, and malignancy. Systemic diseases such as cardiac failure, hypertension, and renal insufficiency may have an adverse effect on survival in FG.

  PDF   |    Full Text | DOI: 10.23937/2469-5742/1510001