The standard treatment of patients with COPD comprises β2-agonists and anticholinergics. Both drugs exert similar effects in terms of bronchodilation but in the clinical use we observed that some patients reported a stable degree or even an increase of dyspnea after the administration of β2-agonists compared to anticholinergics....

Epilepsy is the most common chronic neurological condition in humans and dogs. Unexplained death is up to three times greater in epileptic humans than the general population with less definitive but supportive evidence of this trend in dogs....