The Dahl salt-sensitive rat is a well-established model to study essential hypertension. We fist described a subgroup of these rats based on the unique response pattern in systolic blood pressure during the fist weeks of exposure to a high salt diet that included cataract formation. We classified this group as cataractprone Dahl salt-sensitive rat. We also were able to predict and prevent cataract formation in these rats. Further studies showed an inhibition of lens Na, K-ATPase activity which m...

With great pleasure, I welcome you to the inaugural issue of the International Archives of Translational Medicine. The rapid progress in basic medical research is constantly reframing the paradigm how we prevent, diagnose and treat human diseases....