Cauliflower Outgrowths on an Amputation Stump
Farah El Hadadi, Line Mezni, Kaoutar Znati, Meriem Meziane, Leila Benzekri and Karima Senouci
Article Type: Case Report | First Published: August 30, 2021
Pseudo-epitheliomatous hyperplasia (PEH) is a histopathological reaction due to various stimuli, which includes trauma, infection, inflammation, neoplasia. We report a case of a patient with cauliflower outgrowths on an amputation stump simulating a squamous cell carcinoma. 62-year-old patient, diabetic on insulin therapy for 20 years, complicated by arteriopathy and diabetic neuropathy; who benefited from a trans-tibial amputation with prosthesis wear for 6 years. He consults in dermatology for...
Systemic Quinolones and Risk of Acute Liver Failure II: Systematic Review of Clinical Trials
Mohamed Kadry Taher, Mohamed Habsah, Lise Bjerre, Franco Momoli, Donald Mattison and Daniel Krewski
Article Type: Review Article | First Published: August 30, 2021
Quinolones are a class with four generations of synthetic antibiotics characterized by a unique mechanism of action, broad spectrum, potent pharmacologic properties and reasonable safety profile. Their global and growing popularity has been accompanied by an increase in the emergence of antimicrobial resistance and occurrence of unexpected adverse reactions. Nevertheless, physicians continue to prescribe these drugs on an increasing scale, irrespective of the availability of other treatment alte...