Clinical Medical

Reviews and Case ReportsISSN: 2378-3656


 Open Access DOI:10.23937/2378-3656/1410198

Vesicular Monoamine Transporter Type 2 (VMAT2) Inhibitors in the Management of Tardive Dyskinesia

Lillian L Smith Mosley, Juan F Mosley II, Jessica R Fleischfresser and Tiffani Reed

Article Type: Review Article | First Published: December 30, 2017

Neuroleptic medications are prescribed for the management of mental, gastrointestinal, and neurological disorders. These disorders occur via over-excitation of dopamine in the brain. When neuroleptics are used, dopamine receptors are blocked reducing the excitation. Thus, the disorder becomes controlled. The long-term use of neuroleptics can result in a misfire of the neurons of the brain causing tardive dyskinesia (TD), an irreversible chronic condition of spontaneous movements....

 Open Access DOI:10.23937/2378-3656/1410197

Diagnostic Dilemma of a Mature Parapharyngeal Teratoma in an Infant

Maria Cui Ying Pang and Tan Kun Kiaang

Article Type: Case Report | First Published: December 23, 2017

Cervical and parapharyngeal teratomas are rare but possible causes for respiratory distress in neonates. They can also present as cystic masses in the neck and can be clinically indistinguishable from lymphatic malformations. Physicians must be cognizant of teratoma as an alternate diagnosis when faced with a cystic neck lesion that responds poorly to injection sclerotherapy. We present a case of a parapharyngeal teratoma which was initially diagnosed and treated as a lymphatic malformation....

 Open Access DOI:10.23937/2378-3656/1410196

Management of Congenital Afibrinogenemia: Report of Two Cases

I Alharbi, A Algethami and T Almteri

Article Type: Case Report | First Published: December 22, 2017

Fibrinogen (Factor I) is an essential factor in the coagulation cascade. The activation of prothrombin to thrombin by Factor X is followed by the activation of fibrinogen. In turn, thrombin converts fibrinogen to fibrin, which is the end target of both extrinsic and intrinsic pathways. A deficiency in fibrinogen results in the tendency to bleed....

Volume 4
Issue 12